α-Hydroxy Acid Oxidase: Localization in Renal Microbodies

Abstract

Differential and density equilibrium centrifugation have established the presence of α-hydroxy acid oxidase in microbodies of the kidney of the rat. The enzyme has been demonstrated in cells of the distal convoluted tubule by a microscopic cytochemical method. This enzyme, like certain others in microbodies, produces hydrogen peroxide.