Concepedia

ERα negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor

Fan Jiang, Wenjin Yin, Jin-Song Lu, Lei Wang, Jiong Wu, Feng-Ying Wu, Gen-Hong Di, Zhen‐Zhou Shen, Zhi-Min Shao

Journal of Cancer Research and Clinical Oncology · 2008 · 124 citations · 20 references

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20

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

Elizabeth E. Cameron, Kurtis E. Bachman, Sanna Myöhänen et al. · Nature Genetics · 1999 · 1.9K citations

, , +12

Mechanisms of Tamoxifen Resistance: Increased Estrogen Receptor-HER2/neu Cross-Talk in ER/HER2-Positive Breast Cancer

Jianzhong Shou, Suleiman Massarweh, C. K. Osborne et al. · JNCI Journal of the National Cancer Institute · 2004 · 1.2K citations · Full text

, , +17

Number of CpG islands and genes in human and mouse.

Francisco Antequera, Adrian Bird · Proceedings of the National Academy of Sciences · 1993 · 988 citations

, , +13

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo.

Lisa M. Butler, David B. Agus, Howard I. Scher et al. · PubMed · 2000 · 617 citations

, , +13

Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

David M. Vigushin, Simak Ali, Paul Pace et al. · PubMed · 2001 · 442 citations

, , +10