Concepedia

Tetrahydrobiopterin Regulates Superoxide and Nitric Oxide Generation by Recombinant Endothelial Nitric Oxide Synthase

Robert Wever, Thea van Dam, H.J.M. van Rijn, Flip de Groot, Ton J. Rabelink

Biochemical and Biophysical Research Communications · 1997 · 281 citations · 15 references

Concepts

Redox SignalingBiochemistryReactive Nitrogen SpeciePhysiologyEndothelial DysfunctionTetrahydrobiopterin Regulates SuperoxideVascular BiologyRedox BiologyNitric Oxide GenerationReactive Oxygen SpecieMedicineAtherosclerosisNitrosative StressOxidative Stress

References

15

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

Patrick Vallance, Joe Collier, Salvador Moncada · The Lancet · 1989 · 1.6K citations

Hypertension, Vascular Disease, Cardiovascular Disease +8

Generation of superoxide by purified brain nitric oxide synthase.

Sovitj Pou, Wanida S. Pou, David S. Bredt et al. · Journal of Biological Chemistry · 1992 · 753 citations · Full text

Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

Erik S.G. Stroes, J Kastelein, Francesco Cosentino et al. · Journal of Clinical Investigation · 1997 · 586 citations · Full text

Hypertension, Hyperlipidemia, Endothelial Function +18

Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase

Burghard Heinzel, Michael John, Peter Klatt et al. · Biochemical Journal · 1992 · 534 citations · Full text

Redox Biology, Social Sciences, Oxidative Stress +20

Native Low-Density Lipoprotein Increases Endothelial Cell Nitric Oxide Synthase Generation of Superoxide Anion

Kirkwood A. Pritchard, Laura Groszek, David M. Smalley et al. · Circulation Research · 1995 · 475 citations