The Stripped Basophil Histamine Release Bioassay as a Tool for the Detection of Allergen-Specific IgE in Serum

Abstract

The stripped basophil histamine release bioassay is useful to complement and extend serological detection of allergen-specific IgE. Especially with sera containing IgE against minor components, this assay is more suitable than the RAST. Furthermore, in this assay, the dependency of IgE and of allergen-specific IgE in reactions can be studied in more detail.