Publication | Closed Access
Reconstructing x-ray fluorescence microtomograms
124
Citations
12
References
2001
Year
EngineeringMicroscopyX-ray Fluorescence MicrotomographyX-ray FluorescencePhoton-counting Computed TomographyNuclear MedicineBiophysicsRadiologyX-ray Fluorescence MicrotomogramsMedical ImagingHigh SensitivitySynchrotron RadiationRadiographic ImagingFluorescence MicroscopyX-ray DiffractionBiomedical ImagingFluorescence RadiationMedicineX-ray Optic
X-ray fluorescence microtomography allows one to map element distributions inside a sample with high sensitivity and resolutions in the micrometer range. Quantitative reconstruction of the element concentrations from the fluorescence data requires correction for the attenuation inside the sample. However, the attenuation of the fluorescence radiation is not directly accessible by experiment. The method described self-consistently estimates this attenuation and allows one to reconstruct relative concentrations. This is demonstrated on numerical as well as experimental data. A measure for the quality of the reconstruction is given.
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