Toxicity after intermittent inhalation of nitrous oxide for analgesia

Abstract

A mixture of nitrous oxide and oxygen in equal proportions (Entonox or Equanox) is an effective analgesic and is considered safe with minimal side effects. The mixture is ideal for treating short term pain. We report a serious neurological problem in a patient using such a mixture to control pain from the daily packing of a large perineal cavity.