EFFECTS OF PROPRANOLOL ON GASTRIC SECRETION IN ALBINO RATS

Abstract

1 Effects of graded doses of propranolol have been studied on gastric secretion and gastric ulcers in pylorus-ligated rats.2 A dose-dependent action of propranolol was observed; small doses increased total volume, acid output and pepsin secretion along with an increase in the incidence of ulcers but high doses were inhibitory.