Stoichiometries of transferrin receptors 1 and 2 in human liver

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

John N. Feder, Andreas Gnirke, Zenta Tsuchihashi et al. · Nature Genetics · 1996 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis

George Papanikolaou, Mark Samuels, E H Ludwig et al. · Nature Genetics · 2003 · 976 citations

Medicine, Genetics, Molecular Genetics +14

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

Antonella Roetto, George Papanikolaou, Marianna Politou et al. · Nature Genetics · 2002 · 861 citations

Life Sciences, Molecular Biology, Pathobiology +12

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

John N. Feder, David M. Penny, Alivelu Irrinki et al. · Proceedings of the National Academy of Sciences · 1998 · 838 citations

Life Sciences, Genetics, Molecular Biology +15

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22

Clara Camaschella, Antonella Roetto, Marco De Gobbi et al. · Nature Genetics · 2000 · 807 citations

Life Sciences, Genetics, Molecular Genetics +7