Synthesis and binding affinities of methylvesamicol analogs for the acetylcholine transporter and sigma receptor

Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogs of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol)

Gary A. Rogers, Stanley M. Parsons, D. C. Anderson et al. · Journal of Medicinal Chemistry · 1989 · 237 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Function of sigma1 receptors in Parkinson's disease

Masahiro Mishina, Kiichi Ishiwata, Kenji Ishii et al. · Acta Neurologica Scandinavica · 2005 · 146 citations

Life Sciences, Neurology, Neuroscience +17

In vivo mapping of cholinergic neurons in the human brain using SPECT and IBVM.

Dietmar Kuhl, R A Koeppe, Jeffrey A. Fessler et al. · PubMed · 1994 · 118 citations

Life Sciences, Neuroscience, Pharmacology +14

Rapid Coupling of Methyl Iodide with Aryltributylstannanes Mediated by Palladium(0) Complexes: A General Protocol for the Synthesis of ¹¹CH₃‐Labeled PET Tracers

Masaaki Suzuki, Hisashi Doi, Margareta Björkman et al. · Chemistry - A European Journal · 1997 · 78 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

A radiotracer for mapping cholinergic neurons of the brain

Yong Woon Jung, Marcian E. Van Dort, David L. Gildersleeve et al. · Journal of Medicinal Chemistry · 1990 · 71 citations

Life Sciences, Neurobiology, Neuroscience +12