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Bispyrene-Conjugated 2′-O-Methyloligonucleotide as a Highly Specific RNA-Recognition Probe
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2002
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GeneticsMolecular BiologyMolecular GeneticsEpigeneticsNucleic Acid BiomarkersNucleic Acid ChemistryFluorescence ProbeRna Structure PredictionRna BiologyTranslatomicsOligonucleotideRna TransportGene ExpressionCell BiologyStructural BiologyComplementary RnaChromatinNatural SciencesNucleic Acid BiochemistryMedicineLiving Cell
In the living cell is where the authors hope to elucidate the structure of RNA by using their bispyrene-conjugated 2′-O-methyloligoribonucleotide (OMUpy2-I) fluorescence probe, to detect the hybridization with complementary RNA. The picture shows irradiated I) single-stranded OMUpy2-I, II) hybrid of OMUpy2-I with oligoRNA, and III) OMUpy2-I and oligoDNA. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z19064_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.