Pharmacology of mitoxantrone: mode of action and pharmacokinetics

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

Medicine, Molecular Biology, Pharmacology +17

Agar suspension culture for the selective assay of cells transformed by polyoma virus

Ian Macpherson, Luc Montagnier · Virology · 1964 · 1.3K citations

Life Sciences, Cell Biology, Molecular Virology +9

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

K M Tewey, G L Chen, Eric M. Nelson et al. · Journal of Biological Chemistry · 1984 · 888 citations · Full text

Medicine, Oncology, Pharmacology +14

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

Matthews O. Bradley, Kurt W. Kohn · Nucleic Acids Research · 1979 · 572 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

Eric M. Nelson, K M Tewey, Leroy F. Liu · Proceedings of the National Academy of Sciences · 1984 · 562 citations

Medicine, Molecular Biology, Pharmacology +15