The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combined with Docetaxel - Concepedia

Concepedia

Publication | Open Access

The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combined with Docetaxel

DOI Full Paper Access

241

Citations

31

References

2008

Year

Nikolas K. Haass, Katrin Sproesser, Thiennga K. Nguyen, Rooha Contractor, Calvo Medina, Katherine L. Nathanson, Meenhard Herlyn, Keiran S.M. Smalley

Clinical Cancer Research

Abstract

Inhibition of MEK is cytostatic as a monotherapy in melanoma, but cytotoxic when combined with docetaxel.

References

	Year	Citations

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