National Journal of Maxillofacial Surgery · 2013 · 44 citations · 4 references
Life SciencesImmunologyPharmacologyImmunopathologyInnate ImmunityOral ImmunologyAnti-inflammatory PharmacologyImmunosuppressionMedicinal PlantsNatural Killer Cell FunctionKeratocyte ActivationMedicinal Herbs
Turmeric is dried rhizome of the perennial herbs curcumalonga. It is called Haldi in Hindi, turmeric in English, ukon in Japanese. It has been used in Asian Medicine since the second millennium BC. It's utility is referred to in the ancient Hindu script the Ayurveda. Pathogenesis of the OLP should be taken in consideration for the treatment point of view. The Cell mediated immunity to secondary antigenic change in oral mucous membrane is thought to play a major role in its pathogenesis modified keratocyte surface antigens are the primary target for cytotoxic cellular response. Curcumin also been shown to have immune modulatory effect involving activation of host macrophages and natural killer cells and modulation of lymphocytes mediated function.
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Giovanni Lodi, Crispian Scully, M Carrozzo et al. · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · 2004 · 467 citations
Oral lichen planus: clinical presentation and management.
Paul C. Edwards, Robert Kelsch · PubMed · 2002 · 241 citations · Full text