Concepedia

Absence of Polymerase Protein in Virions of Alpha-Type Rous Sarcoma Virus

Hidesaburô Hanafusa, David Baltimore, Donna Smoler, Kenneth F. Watson, A. Yaniv, S. Spiegelman

Science · 1972 · 75 citations · 12 references

DOI

Concepts

Abstract

Noninfectious particles of a mutant of Rous sarcoma virus failed to exhibit DNA polymerase activity even with the use of the most sensitive synthetic template-primer complexes. A neutralization blocking test against antibody to DNA polymerase revealed that these mutants did not contain protein immunologically related to the DNA polymerase.

References

12

Purification of the DNA polymerase of avian myeloblastosis virus

Daniel Kacian, Kenneth F. Watson, Arsène Burny et al. · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · 1971 · 314 citations

, , +14

Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses

S. Spiegelman, Arsène Burny, M.R. Das et al. · Nature · 1970 · 294 citations

, , +14

Purification and Properties of Deoxyribonucleic Acid Polymerase from Nuclei of Sea Urchin Embryos

Lawrence A. Loeb · Journal of Biological Chemistry · 1969 · 249 citations · Full text

, , +12

Primer Requirement and Template Specificity of the DNA Polymerase of RNA Tumor Viruses

David Baltimore, Donna Smoler · Proceedings of the National Academy of Sciences · 1971 · 229 citations · Full text

, , +15

Synthetic DNA–RNA Hybrids and RNA–RNA Duplexes as Templates for the Polymerases of the Oncogenic RNA Viruses

S. Spiegelman, Arsène Burny, M.R. Das et al. · Nature · 1970 · 210 citations · Full text

, , +16