Increased Turnover of Cerebral Norepinephrine during Rebound of Paradoxical Sleep in the Rat

Abstract

Changes in turnover of cerebral norepinephrine, as measured after intracisternal administration of the H(3) amine, have been studied in rats during selective paradoxical sleep deprivation and its following rebound. Experiments were performed under neurophysiological control. A marked increase of turnover of norepinephrine is associated with the augmentation of paradoxical sleep characteristic of the rebound period.