Correlation between MET Gene Copy Number by Silver In Situ Hybridization and Protein Expression by Immunohistochemistry in Non-small Cell Lung Cancer

<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi et al. · Science · 2007 · 4.5K citations · Full text

Medicine, Oncology, Pharmacology +17

Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer

C. Patrick, Ramasamy Jagadeeswaran, Simha Jagadeesh et al. · Cancer Research · 2005 · 578 citations

Medicine, Oncology, Pharmacology +14

Increased <i>MET</i> Gene Copy Number Negatively Affects Survival of Surgically Resected Non–Small-Cell Lung Cancer Patients

Federico Cappuzzo, Antonio Marchetti, Margaret C. Skokan et al. · Journal of Clinical Oncology · 2009 · 551 citations · Full text

Medicine, Molecular Genetics, Oncology +15

Activity of Crizotinib (PF02341066), a Dual Mesenchymal-Epithelial Transition (MET) and Anaplastic Lymphoma Kinase (ALK) Inhibitor, in a Non-small Cell Lung Cancer Patient with De Novo MET Amplification

Sai‐Hong Ignatius Ou, Eunice L. Kwak, Christina T. Siwak-Tapp et al. · Journal of Thoracic Oncology · 2011 · 439 citations

Medicine, Oncology, Pharmacology +17

Activation of MET by Gene Amplification or by Splice Mutations Deleting the Juxtamembrane Domain in Primary Resected Lung Cancers

Ryoichi Onozato, Takayuki Kosaka, Hiroyuki Kuwano et al. · Journal of Thoracic Oncology · 2009 · 324 citations

Medicine, Molecular Biology, Oncology +15