Methylphenidate and cocaine have a similar in vivo potency to block dopamine transporters in the human brain

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

Mary C. Ritz, R. J. Lamb, Steven R. Goldberg et al. · Science · 1987 · 2.2K citations

Medicine, Neuroscience, Pharmacology +14

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [ <i>N</i> - ¹¹ C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

Jean Logan, Joanna S. Fowler, Nora D. Volkow et al. · Journal of Cerebral Blood Flow & Metabolism · 1990 · 1.5K citations

Pharmacy, Nuclear Medicine, Pharmacology +16

Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate

Nora D. Volkow, Gene Jack Wang, Joanna S. Fowler et al. · American Journal of Psychiatry · 1998 · 891 citations

Medicine, Neuroscience, Pharmacology +17

Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects

Nora D. Volkow, G.-J. Wang, Joanna S. Fowler et al. · Nature · 1997 · 856 citations

Nursing, Neurobiology, Neuroscience +14

Relationship between subjective effects of cocaine and dopamine transporter occupancy

Nora D. Volkow, G J Wang, Marian W. Fischman et al. · Nature · 1997 · 654 citations

Medicine, Neurobiology, Neuroscience +13