Stereoselective Synthesis of <i>myo</i>-Inositol via Ring-Closing Metathesis: A Building Block for Glycosylphosphatidylinositol (GPI) Anchor Synthesis

Abstract

Here we report a concise stereoselective synthesis of myo-inositol via ring-closing metathesis. A readily available bis-Weinreb amide of D-tartrate served as a key intermediate. [reaction: see text]