Concepedia

Inhibition of RNAse A family enzymes prevents degradation and loss of silencing activity of siRNAs in serum

Jörg Haupenthal, Christina Baehr, Simone Kiermayer, Stefan Zeuzem, Albrecht Piiper

Biochemical Pharmacology · 2006 · 152 citations · 35 references

DOI

Concepts

References

35

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

, , +14

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

Scott M. Hammond, Emily Bernstein, David Beach et al. · Nature · 2000 · 3K citations

, , +14

Asymmetry in the Assembly of the RNAi Enzyme Complex

Dianne S. Schwarz, György Hutvágner, Tingting Du et al. · Cell · 2003 · 2.8K citations · Full text

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