Chemistry Letters · 1996 · 63 citations · 6 references
Natural SciencesMarine BiologyMedicinal ChemistryDrug DiscoveryMarine Bioactive CompoundsMarine Drug DiscoveryMarine Natural ProductsMarine PharmacologyBioactive Compounds From Marine SpongesMarine Sponge MetabolitesSponges As Drug SourcesSponges-derived Metabolites
Abstract Two new cytotoxic macrolides, latrunculin S and neolaulimalide, have been isolated from the sponge Fasciospongia rimosa, and their structures determined by NMR and chemical correlation with known congeners.
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Latrunculins: Novel Marine Toxins That Disrupt Microfilament Organization in Cultured Cells
Ilan Spector, Nava R. Shochet, Yoel Kashman et al. · Science · 1983 · 759 citations
Latrunculins: NMR study, two new toxins and a synthetic approach
Yoel Kashman, A. Groweiss, R. LIDOR et al. · Tetrahedron · 1985 · 57 citations