Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.6K citations · Full text

Epigenetic Change, Genetics, Dna Methylation +21

Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

Qing-Lin Li, Kosei Ito, Chohei Sakakura et al. · Cell · 2002 · 1K citations · Full text

Tumor Biology, Oncology, Causal Relationship +10

Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-β and bone morphogenetic protein

Kyeong‐Sook Lee, Seung-Hyun Hong, Suk‐Chul Bae · Oncogene · 2002 · 342 citations

Developmental Biology, Signal Transduction, Bone Morphogenic Protein +8

Allele-Specific Chromosome 3p Deletions Occur at an Early Stage in the Pathogenesis of Lung Carcinoma

Jaclyn Y. Hung · JAMA · 1995 · 339 citations

K-ras mutations and RASSF1A promoter methylation in colorectal cancer

Manon van Engeland, Guido M.J.M. Roemen, Mirian Brink et al. · Oncogene · 2002 · 182 citations · Full text

Tumor Biology, Medicine, Colorectal Cancer +6