Concepedia

Simultaneous suppression of multidrug resistance and antiapoptotic cellular defense induces apoptosis in chemoresistant human acute myeloid leukemia cells

Xiaofang Wang, Chun Wang, Youwen Qin, Shi-Ke Yan, Yanrong Gao

Leukemia Research · 2006 · 22 citations · 12 references

DOI

Concepts

References

12

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations · Full text

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IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

Quinn L. Deveraux · The EMBO Journal · 1998 · 1.4K citations · Full text

, , +14

The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

, , +14

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

Ingo Tamm, Yi Wang, Edward A. Sausville et al. · PubMed · 1998 · 1.3K citations

, , +17

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

Quinn L. Deveraux · The EMBO Journal · 1999 · 756 citations · Full text

, , +10