Clonidine induces rat aorta relaxation by nitric oxide-dependent and -independent mechanisms

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

K+ is an endothelium-derived hyperpolarizing factor in rat arteries

G. Edwards, Kim A. Dora, M J Gardener et al. · Nature · 1998 · 1.1K citations

Life Sciences, Pharmacology, Physiology +13

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

Robert M. Rapoport, Ferid Murad · Circulation Research · 1983 · 933 citations · Full text

Medicine, Pharmacology, Physiology +12

Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells

Cécile Eglème, Théophile Godfraind, Robert C. Miller · British Journal of Pharmacology · 1984 · 225 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Role of potassium channels in endothelium‐dependent relaxation resistant to nitroarginine in the rat hepatic artery

Peter M. Zygmunt, Edward D. Högestätt · British Journal of Pharmacology · 1996 · 219 citations · Full text

Medicine, Pharmacology, Ion Channel Biophysics +15