Two new miR‐16 targets: caprin‐1 and HMGA1, proteins implicated in cell proliferation

Abstract

Taken together, our data demonstrated that miR-16 can negatively regulate two new targets, HMGA1 and caprin-1, which are involved in cell proliferation. In addition, we also showed that the inhibition of cyclin E expression was due, at least in part, to a decrease in its mRNA stability.