Effect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblast

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics · 2003 · 2K citations

Life Sciences, Cell Biology, Physiology +14

<b> <i>PKD2</i> </b> , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein

Toshio Mochizuki, Guanqing Wu, Tomohito Hayashi et al. · Science · 1996 · 1.4K citations

Medicine, Genetics, Molecular Genetics +17

The Polycystic Kidney Disease Proteins, Polycystin-1, Polycystin-2, Polaris, and Cystin, Are Co-Localized in Renal Cilia

Bradley K. Yoder, Xiaoying Hou, Lisa M. Guay‐Woodford · Journal of the American Society of Nephrology · 2002 · 939 citations

Medicine, Cell Biology, Molecular Biology +16

Bending the MDCK Cell Primary Cilium Increases Intracellular Calcium

K. R. Spring · The Journal of Membrane Biology · 2001 · 814 citations

Life Sciences, Biophysics, Cell Biology +14

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca ²⁺ -permeable nonselective cation channel

Silvia González‐Perrett, Kee‐Tae Kim, Cristina Ibarra et al. · Proceedings of the National Academy of Sciences · 2000 · 447 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16