EFFECT OF PROSTAGLANDIN ON THE SECRETION OF HUMAN GROWTH HORMONE

Haruo Itô, Goichi Momose, Takashi Katayama, H Takagishi, Lumi Ito, Hironori Nakajima, Yoshisato Takei

The Journal of Clinical Endocrinology & Metabolism · 1971 · 44 citations · 1 references

Concepts

Abstract

Intravenous drip infusion of PGE1 in man induced a marked increase of GH secretion. Stimulation of HGH secretion by PGE1 administration is possibly explained by the assumption of a direct or indirect action of PGE1 on the anterior pituitary increasing cyclic AMP, consequently releasing HGH. Intravenous infusion of PGE1 appears to be useful as a method of testing the secretory activity of GH.

References

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