Emergency Medicine Journal · 1998 · 11 citations · 8 references
PharmacyEmergency MedicineToxicologyPatient SafetyPoisoning DiagnosisPoisoning ManagementEmergency Response To PoisoningPoison InformationEmergency Management Of PoisoningPoison Control GuidanceReference NomogramsTreatment Nomograms
OBJECTIVE: To assess the impact of the treatment guidelines on the management of paracetamol self poisoning in accident and emergency (A&E) departments. METHODS: 24 A&E departments in Wales and England provided details of their management of paracetamol poisoning before and after the distribution of national treatment guidelines to all A&E departments in the United Kingdom. RESULTS: Significant increases were seen in the availability of formal written policies, the display of treatment nomograms, the recommendation to treat beyond 16 hours after ingestion, and to use a lower line on the treatment nomogram for patients at special risk of paracetamol induced liver damage. CONCLUSIONS: Regularly updated guidelines in the management of paracetamol poisoning should be displayed in A&E departments so that medical and nursing personnel have access to the best current information on the treatment of poisoning with this frequently used drug.
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SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS
Roland Buhl, Kenneth J. Holroyd, Andrea Mastrangeli et al. · The Lancet · 1989 · 725 citations
Hepatotoxicity due to repeated intake of low doses of paracetamol
L. S. Eriksson, Ulrika Broomé, M. Kalin et al. · Journal of Internal Medicine · 1992 · 123 citations