Concepedia

Improved Procedure for the Reduction of N-Acyloxazolidinones

Thomas D. Penning, Stevan W. Djurić, Richard A. Haack, Vincent J. Kalish, Julie M. Miyashiro, Bruce W. Rowell, Stella S. Yu

Synthetic Communications · 1990 · 143 citations · 9 references

DOI

Concepts

Abstract

Abstract Lithium borohydride in the presence of one equivalent of water has been found to be an efficient agent for the reduction of sterically hindered acyloxazolidinones to the corresponding primary alcohol.

References

9

Enantioselective aldol condensations. 2. Erythro-selective chiral aldol condensations via boron enolates

David A. Evans, Javier Bartrolí, Thomas L. Shih · Journal of the American Chemical Society · 1981 · 1.5K citations

, , +7

Asymmetric Diels-Alder cycloaddition reactions with chiral .alpha.,.beta.-unsaturated N-acyloxazolidinones

David A. Evans, Kevin T. Chapman, John J. Bisaha · Journal of the American Chemical Society · 1988 · 635 citations

, , +6

Contrasteric carboximide hydrolysis with lithium hydroperoxide

David A. Evans, Thomas C. Britton, J. A. ELLMAN · Tetrahedron Letters · 1987 · 458 citations

, , +5

Asymmetric oxygenation of chiral imide enolates. A general approach to the synthesis of enantiomerically pure .alpha.-hydroxy carboxylic acid synthons

David A. Evans, M. M. MORRISSEY, Roberta L. Dorow · Journal of the American Chemical Society · 1985 · 255 citations

, , +8

Electrophilic azide transfer to chiral enolates. A general approach to the asymmetric synthesis of .alpha.-amino acids

David A. Evans, Thomas C. Britton · Journal of the American Chemical Society · 1987 · 149 citations

, , +12