The Journal of Physical Chemistry B · 1999 · 153 citations · 18 references
Natural SciencesBiochemistryChemistryDrug DeliveryMembrane TraffickingSupramolecular ChemistryLipid Bilayer StructureMembrane Self-assemblyPhotochemical KineticsPhotochemistrySurfactantsVesicle FormationAnionic SurfactantsIntraluminal Vesicle FormationLipid VesiclesMicroscopic CharacterizationMolecular Switching BehaviorPhotoisomerization KineticsVesicle Formation KineticsVesicle Self-assembly
Formation and disruption of vesicles could be photochemically controlled in aqueous mixtures of a “photo-switchable” azobenzene-modified cationic surfactant (4-butylazobenzene-4‘-(oxyethyl)trimethylammonium bromide; AZTMA) and an anionic surfactant (sodium dodecylbenzenesulfonate; SDBS). Vesicles were formed spontaneously in a wide composition range in aqueous trans -AZTMA/SDBS mixtures. AZTMA molecules constituting vesicles underwent reversible trans−cis photoisomerization upon alternate UV and visible-light irradiation. Transmission electron microscopic observations via freeze replica technique demonstrated the disruption of the vesicles into larger aggregates (precipitate) with UV-light irradiation (cis formation) and the following visible-light irradiation (trans formation) resulted in vesicle reformation. Furthermore, the release rate of aqueous compounds encapsulated in vesicles was shown to be photochemically controllable in the present AZTMA/SDBS mixed system.
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The Fluid Mosaic Model of the Structure of Cell Membranes
Sherwin J. Singer, Garth L. Nicolson · Science · 1972 · 9K citations
Spontaneous Vesicle Formation in Aqueous Mixtures of Single-Tailed Surfactants
Eric W. Kaler, A. K. Murthy, B. E. Rodriguez et al. · Science · 1989 · 1.2K citations