Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Ann M. Sheehy, Nathan Gaddis, Jonathan Choi et al. · Nature · 2002 · 2.3K citations

Life Sciences, Microbiology, Molecular Biology +15

HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots

A. R. W. Schröder, Paul Shinn, Huaming Chen et al. · Cell · 2002 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

Bastien Mangeat, Priscilla Turelli, Gersende Caron et al. · Nature · 2003 · 1.5K citations · Full text

Life Sciences, Molecular Genetics, Molecular Medicine +17

DNA Deamination Mediates Innate Immunity to Retroviral Infection

Reuben S. Harris, Kate N. Bishop, Ann M. Sheehy et al. · Cell · 2003 · 1.3K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

Xianghui Yu, Yunkai Yu, Bindong Liu et al. · Science · 2003 · 1.2K citations

Life Sciences, Biology, Molecular Biology +13