Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Ann M. Sheehy, Nathan Gaddis, Jonathan Choi et al. · Nature · 2002 · 2.3K citations

Molecular Virology, Human Retrovirus, Pathogenesis +12

HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots

A. R. W. Schröder, Paul Shinn, Huaming Chen et al. · Cell · 2002 · 1.8K citations · Full text

Viral Replication, Functional Genomics, Hiv-1 Integration +11

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

Bastien Mangeat, Priscilla Turelli, Gersende Caron et al. · Nature · 2003 · 1.5K citations · Full text

Medicine, Human Retrovirus, Immunology +9

DNA Deamination Mediates Innate Immunity to Retroviral Infection

Reuben S. Harris, Kate N. Bishop, Ann M. Sheehy et al. · Cell · 2003 · 1.3K citations · Full text

Retroviral Infection, Viral Persistence, Human Retrovirus +4

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

Xianghui Yu, Yunkai Yu, Bindong Liu et al. · Science · 2003 · 1.2K citations

Molecular Virology, Vif Mutant, Human Retrovirus +14