The polysaccharide fucoidan inhibits microvascular thrombus formation independently from P‐ and <scp>l</scp>‐selectin function <i>in vivo</i>

Abstract

Taken together, our novel findings suggest that fucoidan effectively prevents microvascular thrombus formation induced by endothelial damage in arterioles and venules in vivo. This protective effect of fucoidan is not attributable to inhibition of P- and L-selectin function but may instead be related to the anticoagulative capacity of fucoidan.