Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

Y. Kubota, Rachel A. Nash, Arne Klungland et al. · The EMBO Journal · 1996 · 774 citations · Full text

Xrcc1 Protein, Genome Instability, Natural Sciences +9

Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.

Mei-Ling Shen, I M Jones, H.W. Mohrenweiser · PubMed · 1998 · 774 citations

Susceptibility Alleles, Dna Damage, Genetics +16

XRCC1 Polypeptide Interacts with DNA Polymerase   and Possibly Poly (ADP-Ribose) Polymerase, and DNA Ligase III Is a Novel Molecular 'Nick-Sensor' In Vitro

Keith W. Caldecott, Saïd Aoufouchi, Peter Johnson et al. · Nucleic Acids Research · 1996 · 609 citations · Full text

XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency.

Ruth M. Lunn, R G Langlois, Ling‐Ling Hsieh et al. · PubMed · 1999 · 570 citations

Allelic Variant, Xrcc1 Polymorphisms, Genetic Disorder +14

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.

Larry H. Thompson, Kerry W. Brookman, Nigel J. Jones et al. · Molecular and Cellular Biology · 1990 · 401 citations

Dna Damage, Xrcc1 Gene, Genetics +20