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On-column nitrosation of amines observed in liquid chromatography impurity separations employing ammonium hydroxide and acetonitrile as mobile phase

Chemical EngineeringEngineeringSeparation ScienceMobile PhaseOn-column NitrosationOrganic ChemistryAnalytical ChemistryAmmonium HydroxideLiquid ChromatographyChemistryChromatographic AnalysisMedicineAdvanced SeparationChromatographyDrug Analysis