Neocortical seizure foci localization by means of a directed transfer function method

Abstract

Although localization of neocortical-onset seizures is typically challenging, the causal measures employed in this study-namely the directed transfer function-identified generators of the ictal activity that were highly correlated with the cortical regions identified as the seizure-onset zones by the epileptologists. This technique could prove useful in the identification of seizure-specific propagation pathways in the presurgical evaluation of patients with epilepsy.