The structure of lienomycin, a pentaene macrolide antitumor antibiotic. I. The structure of the carbon skeleton and the location of functionalities.

Abstract

The structure of a novel type of pentaene macrolide named lienomycin (I) was established by selected chemical transformations of I followed by MS examination of the products. This report provides evidence on the structure of the carbon skeleton of I and on the location of functionalities.