Contrast media as histamine liberators. II. Histamine release into venous plasma during intravenous urography in man.

Abstract

Plasma histamine levels were determined before and five minutes after intravenous injection of meglumine iothalamate 60% (Conray) in 57 randomly selected patients who underwent intravenous urography. Eighteen of the patients (32%) experienced a reaction to the injection beyond a sensation of warmth