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Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors

Masaharu Uno, Yosuke Koma, Hyun Seung Ban, Hiroyuki Nakamura

Bioorganic & Medicinal Chemistry Letters · 2012 · 42 citations · 24 references

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24

Regulation of hypoxia-inducible factor 1α is mediated by an O <sub>2</sub> -dependent degradation domain via the ubiquitin-proteasome pathway

Eric Huang, Jie Gu, Maureen Schau et al. · Proceedings of the National Academy of Sciences · 1998 · 2.1K citations · Full text

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Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1

Bing‐Hua Jiang, Elizabeth Rue, Guang L. Wang et al. · Journal of Biological Chemistry · 1996 · 1.1K citations · Full text

, , +12

The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity

Andrea Pichler, Andreas Gast, Jacob-S. Seeler et al. · Cell · 2002 · 804 citations · Full text

, , +4

An E3-like Factor that Promotes SUMO Conjugation to the Yeast Septins

Erica S. Johnson, Aseem A. Gupta · Cell · 2001 · 638 citations · Full text

, , +7

SUMO-Specific Protease 1 Is Essential for Stabilization of HIF1α during Hypoxia

Jinke Cheng, Xunlei Kang, Sui Zhang et al. · Cell · 2007 · 607 citations · Full text

, , +10