Antimicrobial Agents and Chemotherapy · 1990 · 170 citations · 15 references
Life SciencesMicrobiologyMolecular BiologyBacteriologyMicrobial BiotechnologyMicrobial GenomicsBacterial GeneticsBeta-lactamase GenesClass B Metallo-beta-lactamasesEscherichia Coli
Bacteroides fragilis TAL3636 produces a class B, Zn2(+)-requiring beta-lactamase. The gene, ccrA, was cloned and expressed in Escherichia coli. The gene was sequenced and shown to share greater than 33% identity with the metalloenzyme from Bacillus cereus 569/H.
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Gunnar von Heijne · Journal of Molecular Biology · 1985 · 2.2K citations
Jeffrey S. Thompson, M H Malamy · Journal of Bacteriology · 1990 · 164 citations