Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

Medicine, Genetics, Oncology +11

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

Yardena Samuels, Luis A. Díaz, Oleg Schmidt‐Kittler et al. · Cancer Cell · 2005 · 919 citations · Full text

Medicine, Cancer Biology, Oncology +16

Mutation of the <b> <i>PIK3CA</i> </b> Gene in Ovarian and Breast Cancer

Ian Campbell, Sarah E. Russell, David Y.H. Choong et al. · Cancer Research · 2004 · 914 citations · Full text

Medicine, Genetics, Oncology +17

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

Sohye Kang, Andreas G. Bader, Peter K. Vogt · Proceedings of the National Academy of Sciences · 2005 · 824 citations · Full text

Medicine, Cancer Biology, Oncology +17

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

Jiwang Zhang, Justin C. Grindley, Tong Yin et al. · Nature · 2006 · 816 citations

Life Sciences, Genetics, Hematology +16