Identification of a susceptibility locus in <i>STAT4</i> for Behçet's disease in Han Chinese in a genome‐wide association study

Abstract

These findings strongly suggest that STAT4 is a novel locus underlying BD. We propose a model in which up-regulation of STAT4 expression and subsequent STAT4-driven production of inflammatory cytokines, such as IL-17, constitute a potential pathway leading to BD.