Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer

Celeste Y. Kang, Wissam J. Halabi, Obaid Chaudhry, Vinh Nguyen, Alessio Pigazzi, Joseph C. Carmichael, Steven Mills, Michael J. Stamos

JAMA Surgery · 2012 · 404 citations · 39 references

Abstract

Anastomotic leak after anterior resection increased mortality rates and health care costs. Weight loss and malnutrition, fluid and electrolyte disorders, male sex, and stoma placement independently increased the risk of leak. Laparoscopy independently decreased the risk of leak. Further studies are needed to delineate the significance of these findings.

References

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