Development of simple and rapid LC–MS/MS method for determination of celecoxib in human plasma and its application to bioequivalence study

Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis

Fred E. Silverstein, Gerald A. Faich, Jay L. Goldstein et al. · JAMA · 2000 · 3.2K citations

Major Role of Human Liver Microsomal Cytochrome P450 2C9 (CYP2C9) in the Oxidative Metabolism of Celecoxib, a Novel Cyclooxygenase-II Inhibitor

Cuyue Tang, Magang Shou, Mei Qin et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 158 citations

Metabolism and Excretion of [14C]Celecoxib in Healthy Male Volunteers

S. K. Paulson, Jeremy D. Hribar, Norman W. Liu et al. · Drug Metabolism and Disposition · 2000 · 146 citations

In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics

Cuyue Tang, Magang Shou, Thomas H. Rushmore et al. · Pharmacogenetics · 2001 · 121 citations

Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites

Julia Kirchheiner, E. St uuml rmer, Christian Meisel et al. · Pharmacogenetics · 2003 · 115 citations

Cyp2c9 Variant Ile359leu, Genotype Cyp2c9, Polymorphic Cytochrome P450 +14