Topological descriptors in modeling the agonistic activity of human A3 adenosine receptor ligands: The derivatives of 2-chloro-N6-substituted-4′-thioadenosine-5′-uronamide

The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells

Vickram Ramkumar, Gary L. Stiles, Michael A. Beaven et al. · Journal of Biological Chemistry · 1993 · 442 citations · Full text

Adenosine Analogs, Mast Cell Disorder, Immunology +18

Inhibition of TNF-α expression by adenosine: role of A3 adenosine receptors

Fereydoun G. Sajjadi, Kensuke Takabayashi, Alan C. Foster et al. · The Journal of Immunology · 1996 · 348 citations · Full text

2-Substitution of N6-Benzyladenosine-5'-uronamides Enhances Selectivity for A3 Adenosine Receptors

Hea O. Kim, Xiao-duo Ji, Suhaib M. Siddiqi et al. · Journal of Medicinal Chemistry · 1994 · 204 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14

Structural Determinants of A₃ Adenosine Receptor Activation:  Nucleoside Ligands at the Agonist/Antagonist Boundary

Zhan‐Guo Gao, Soo‐Kyung Kim, Thibaud Biadatti et al. · Journal of Medicinal Chemistry · 2002 · 137 citations · Full text

Molecular Biology, Pharmacotherapy, Experimental Pharmacology +18

N6-Substituted adenosine derivatives: selectivity, efficacy, and species differences at A3 adenosine receptors

Zhan‐Guo Gao, Joshua B. Blaustein, Ariel S. Gross et al. · Biochemical Pharmacology · 2003 · 134 citations

Molecular Pharmacology, Biochemistry, Functional Selectivity +7