Concepedia

A facile route to flavone and neoflavone backbones via a regioselective palladium catalyzed oxidative Heck reaction

Mehdi Khoobi, Masoumeh Alipour, Samaneh Zarei, Farnaz Jafarpour, Abbas Shafiee

Chemical Communications · 2012 · 140 citations · 33 references

DOI

Concepts

Abstract

A straightforward and atom-economical base-free palladium-catalyzed regioselective direct arylation of coumarins and chromenones is devised. This protocol is compatible with a wide variety of electron-donating and -withdrawing substituents and allows construction of various biologically important flavone and neoflavone backbones.

References

33

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

Rubén Martı́n, Stephen L. Buchwald · Accounts of Chemical Research · 2008 · 2.6K citations

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Surveying Sterically Demanding N-Heterocyclic Carbene Ligands with Restricted Flexibility for Palladium-catalyzed Cross-Coupling Reactions

Sebastian Würtz, Frank Glorius · Accounts of Chemical Research · 2008 · 731 citations

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Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling

Gary A. Molander, Belgin Canturk · Angewandte Chemie International Edition · 2009 · 430 citations · Full text

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The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn

Ashok D. Patil, Alan J. Freyer, Drake S. Eggleston et al. · Journal of Medicinal Chemistry · 1993 · 412 citations · Full text

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Oxidative Palladium(II) Catalysis:  A Highly Efficient and Chemoselective Cross-Coupling Method for Carbon−Carbon Bond Formation under Base-Free and Nitrogenous-Ligand Conditions

Kyung Soo Yoo, Cheol Hwan Yoon, Kyung Woon Jung · Journal of the American Chemical Society · 2006 · 271 citations · Full text

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