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Effect of carbon tetrachloride on gonadal physiology in male rats
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1975
Year
SpermatogenesisFertilityGynecologyVaried IntervalsSemen AnalysisReproductive BiologyReproductive EndocrinologyToxicologyMale InfertilitySevere DamageGametogenesisPublic HealthInfertilityAndrologyEndocrine MechanismGameteHormonal Male ContraceptionEndocrinologyPharmacologyHuman ReproductionCarbon TetrachloridePhysiologyMedicineReproductive Hormone
Carbon tetrachloride was administered to male albino rats for varied intervals. It was found to have no significant adverse effect on spermatogenesis after 10 and 15 days of treatment. Severe damage to the spermatogenic cycle was observed after 20 days of treatment, leading to exfoliation of the germinal epithelium, depletion of germ cells, and shrinkage of the tubules.