Concepedia

Engineering epidermal growth factor for enhanced mitogenic potency

Cartikeya C. Reddy, Salil K. Niyogi, Alan Wells, H Wiley, Douglas A. Lauffenburger

Nature Biotechnology · 1996 · 101 citations · 6 references

DOI

Concepts

References

6

Intracellular Trafficking of Epidermal Growth Factor Family Ligands Is Directly Influenced by the pH Sensitivity of the Receptor/Ligand Interaction

Anthony R. French, Douglas K. Tadaki, Salil K. Niyogi et al. · Journal of Biological Chemistry · 1995 · 244 citations · Full text

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Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

P Chen, Kiran Gupta, Alan Wells · The Journal of Cell Biology · 1994 · 228 citations · Full text

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Receptor-mediated effects on ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor α

Cartikeya C. Reddy, Alan Wells, Douglas A. Lauffenburger · Journal of Cellular Physiology · 1996 · 69 citations

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Proliferative Response of Fibroblasts Expressing Internalization‐Deficient Epidermal Growth Factor (EGF) Receptors Is Altered via Differential EGF Depletion Effect

Cartikeya C. Reddy, Alan Wells, Douglas A. Lauffenburger · Biotechnology Progress · 1994 · 52 citations

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The functional importance of hydrophobicity of the tyrosine at position 13 of human epidermal growth factor in receptor binding

Douglas K. Tadaki, Niyogi Sk · Journal of Biological Chemistry · 1993 · 42 citations · Full text

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