Synthesis of 3′-deoxy-3′-(2-propynyl)thymidine and 3′-cyanomethyl-3′-deoxythymidine, analogs of AZT

The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

Margaret A. Fischl, Douglas D. Richman, Michael H. Grieco et al. · New England Journal of Medicine · 1987 · 3K citations

Life Sciences, Immunology, Pharmacology +16

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.9K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

Robert Yarchoan, Hiroaki Mitsuya, Rose V. Thomas et al. · Science · 1989 · 425 citations

Medicine, Infectious Diseases, Pharmacology +17

Carbon-carbon bond formation via the reaction of trialkylallylstannanes with organic halides

Gary E. Keck, John B. Yates · Journal of the American Chemical Society · 1982 · 270 citations

Natural Sciences, Chemistry, Chemical Kinetics +7

Circulating p24 Antigen Levels and Responses to Dideoxycytidine in Human Immunodeficiency Virus (HIV) Infections

Thomas C. Merigan · Annals of Internal Medicine · 1989 · 213 citations

Pharmacy, Infectious Diseases, Pharmacotherapy +15