A modular system for regeneration of NADcofactors using graphite particles modified with hydrogenase and diaphorase moieties

Holly A. Reeve, Lars Lauterbach, Philip A. Ash, Oliver Lenz, Kylie A. Vincent

Chemical Communications · 2011 · 65 citations · 20 references

Concepts

Abstract

Pyrolytic graphite particles modified with hydrogenase and an NAD(+)/NADH cycling enzyme provide a modular heterogeneous catalyst system for regeneration of oxidised or reduced nicotinamide cofactors using H(2) and H(+) as electron source or sink. Particles can be tuned for cofactor supply under different conditions by appropriate choice of hydrogenase.

References

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