Microtubule Contribution to the Reflectance of the Retinal Nerve Fiber Layer

Abstract

MTs contribute to RNFL reflectance at all wavelengths. Unlike RNFL birefringence, however, which totally disappears after colchicine treatment, about one half of RNFL reflectance remained after colchicine treatment. This result suggests that, in addition to MTs, other mechanisms may contribute to RNFL reflectance.