The dipeptidyl peptidase-IV inhibitor inhibits the expression of vascular adhesion molecules and inflammatory cytokines in HUVECs via Akt- and AMPK-dependent mechanisms

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

Myron I. Cybulsky, Kaeko Iiyama, Hongmei Li et al. · Journal of Clinical Investigation · 2001 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +16

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

Myoung Sook Han, Dae Young Jung, Caroline Morel et al. · Science · 2012 · 624 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Inhibition of Monocyte Adhesion to Endothelial Cells and Attenuation of Atherosclerotic Lesion by a Glucagon-like Peptide-1 Receptor Agonist, Exendin-4

Masayuki Arakawa, Tomoya Mita, Kosuke Azuma et al. · Diabetes · 2010 · 536 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

Zhenggang Yang, Barbara B. Kahn, Hang Shi et al. · Journal of Biological Chemistry · 2010 · 413 citations · Full text

Life Sciences, Cell Biology, Immunology +13

Akt Activity Negatively Regulates Phosphorylation of AMP-activated Protein Kinase in the Heart

Suzanne Kovacic, Carrie-Lynn M. Soltys, Amy Barr et al. · Journal of Biological Chemistry · 2003 · 405 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13